凝集素样氧化低密度脂蛋白受体1（可溶性）(人)酶联试剂盒

产品名称：凝集素样氧化低密度脂蛋白受体1（可溶性）(人)酶联试剂盒

英文名称：Soluble Lectin-like oxidized LDL Receptor 1 (LOX-1) (Human) ELISA Kit

产品编号：SK00006-09

规格：96T

厂家：Aviscera Bioscience

产品介绍：

美国爱威斯生物开发的凝集素样氧化低密度脂蛋白受体1（可溶性）(人)酶联试剂盒

• High Sensitivity

• Monoclonal Antibody Pair Formulated

• Validated by WB & E

• Calibrator: human soluble LOX-1 derived from HEK293

Alternative name: Oxidized Low-density Lipoprotein Receptor 1 (OLR1).
Soluble LOX-1 is a new biomarker of cardiovascular diseases.Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis.

Citations:
"A fermented bean flour extract downregulates LOX-1, CHOP and ICAM-1 in HMEC-1 stimulated by ox-LDL" by Morena Gabriele

Features

• Size: 96 T

  Standard Range: 19.5 - 1250 pg/ml

  Sensitivity: 7.8 pg/ml
  Specficity: human soluble LOX-1 HEK293 derived

  Sample Type: serum or plasma

  Dilution factor: N/A

  Intra-CV: 4-6%

  Inter-CV:8-10%

  Data Sheet: PDF