高敏感性血凝素样氧化低密度脂蛋白受体-1（可溶性）(人)酶联试剂盒

产品名称：高敏感性血凝素样氧化低密度脂蛋白受体-1（可溶性）(人)酶联试剂盒

英文名称：Soluble Lectin-like oxidized LDL Receptor 1 (LOX-1) (Human) Ultrasensitive ELISA Kit

产品编号：SK00006-08

规格：96 T 

厂家：Aviscera Bioscience

产品介绍：

美国爱威斯生物开发的高敏感性血凝素样氧化低密度脂蛋白受体-1（可溶性）(人)酶联试剂盒

• High Sensitivity

• Monoclonal Antibody Pair Formulated

• Calibrator: human sLOX-1 Rec (NS0 derived)

• Validated by western blot and ELISA

Alternative name: Oxidized Low-density Lipoprotein Receptor 1 (OLR1).
Soluble LOX-1 is a new biomarker of cardiovascular research. Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis.

Citations:

Perla-Monserrat Madrigal-Ruíz, et al. "Low CD36 and LOX-1 Levels and CD36 Gene Subexpression Are Associated with Metabolic Dysregulation in Older Individuals with Abdominal Obesity" Journal of Diabetes Research Volume 2016, Article ID 5678946

Features

• Size: 96 T

  Standard Range: 7.8 ~ 500 pg/ml

  Sensitivity: 5 pg/ml
  Specificity: human soluble LOX-1 NS0 derived

  Sample Type: serum or plasma

  Dilution factor: N/A

  Intra-CV: 4-6%

  Inter-CV:8-10%

  Data Sheet:PDF